Retinoic Acid Early Transcript 1E (RAET1E) (AA 150-179) Antikörper

Produktnummer ABIN1881724

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Retinoic Acid Early Transcript 1E (RAET1E) (AA 150-179) Antikörper (ABIN1881724)

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40835

Produktdetails

Bindungsspezifität: AA 150-179

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAET1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the Central region of human RAET1E.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Antigendetails

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Andere Bezeichnung: RAET1E

Hintergrund: Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1, MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a ligand for NKG2D (KLRK1, MIM 611817), which is expressed on the surface of several types of immune cells and is involved in innate and adaptive immune responses (summary by Radosavljevic et al. (2002) [PubMed 11827464] and Cao et al. (2007) [PubMed 17470428]).

Molekulargewicht: 30122

NCBI Accession: NP_001230254, NP_001230256, NP_001230257, NP_631904

UniProt: Q8TD07