Retinoic Acid Early Transcript 1E (RAET1E) (AA 160-210) Antikörper

Produktnummer ABIN6992142

Der Kaninchen Polyklonal anti-Retinoic Acid Early Transcript 1E Antikörper (ABIN6992142) detektiert spezifisch Retinoic Acid Early Transcript 1E in ELISA, WB und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Retinoic Acid Early Transcript 1E (RAET1E) (AA 160-210) Antikörper (ABIN6992142)

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Produktdetails

Bindungsspezifität: AA 160-210

Spezifität: RAET1E antibody is human and mouse reactive. At least four isoforms of RAET1E are known to exist, this antibody will detect all four.

Aufreinigung: RAET1E antibody is affinity chromatography purified via peptide column.

Immunogen: RAET1E antibody was raised against an 18 amino acid peptide near the center of human RAET1E. The immunogen is located within amino acids 160 - 210 of RAET1E.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RAET1E antibody can be used for detection of RAET1E by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RAET1E antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RAET1E antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Antigendetails

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Andere Bezeichnung: RAET1E

Hintergrund: The Retinoic acid early transcript 1E (RAET1E) belongs to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3 (1). Like the related protein RAET1G, RAET1E differs from other RAET1 proteins in that they have type I membrane-spanning sequences at their carboxy termini rather than glycosylphosphatidylinositol anchor sequences (2). RAET1E functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses (1,3).

Molekulargewicht: Predicted: 29 kDa

Observed: 29 kDa

Gen-ID: 135250

NCBI Accession: NP_631904

UniProt: P84103