Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IFITM1 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This IFITM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human IFITM1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Ma, Zhang, Fu, Xia, Zhan, Li, Wang, Wu: "Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).
Mosbruger, Duggal, Goedert, Kirk, Hoots, Tobler, Busch, Peters, Rosen, Thomas, Thio: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, (2010) (PubMed).
Yang, Chen, Lin, Yu, Liu, Wang, Liu, Chen et al.: "Nickel catalysts bearing bidentate alpha-aminoaldimines for ethylene polymerization--independent and cooperative structure/reactivity relationship resulting from unsymmetric square planar..." in: Dalton transactions (Cambridge, England : 2003), Issue 7, pp. 1243-50, (2009) (PubMed).
Target
IFITM1
(Interferon-Induced Transmembrane Protein 1 (IFITM1))
Andere Bezeichnung
IFITM1
Hintergrund
IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.