GSTT2 Antikörper (AA 113-141)

Produktnummer ABIN1881394

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GSTT2 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für GSTT2 Antikörper (AA 113-141) (ABIN1881394)

Target: GSTT2 (Glutathione S-Transferase theta 2 (GSTT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB41723

Produktdetails anti-GSTT2 Antikörper

Bindungsspezifität: AA 113-141

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSTT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human GSTT2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GSTT2 Antikörper (ABIN1881394)

Canova, Richiardi, Merletti, Pentenero, Gervasio, Tanturri, Garzino-Demo, Pecorari, Talamini, Barzan, Sulfaro, Franchini, Muzzolini, Bordin, Pugliese, Macrì, Simonato: "Alcohol, tobacco and genetic susceptibility in relation to cancers of the upper aerodigestive tract in northern Italy." in: Tumori, Vol. 96, Issue 1, pp. 1-10, (2010) (PubMed).

Wang, Chanock, Tang, Li, Edwards, Jedrychowski, Perera: "Effect of gene-environment Interactions on mental development in African American, Dominican, and Caucasian mothers and newborns." in: Annals of human genetics, Vol. 74, Issue 1, pp. 46-56, (2010) (PubMed).

Moyer, Sun, Batzler, Li, Schaid, Yang, Weinshilboum: "Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 3, pp. 811-21, (2010) (PubMed).

Details zu GSTT2

Target: GSTT2 (Glutathione S-Transferase theta 2 (GSTT2))

Andere Bezeichnung: GSTT2

Hintergrund: Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55 % amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

Molekulargewicht: 27506

UniProt: P0CG29

Pathways: Myometrial Relaxation and Contraction, Autophagie