Frataxin Antikörper (N-Term)
(4 Referenzen)-
- Target Alle Frataxin (FXN) Antikörper anzeigen
- Frataxin (FXN)
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Bindungsspezifität
- AA 36-64, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Frataxin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.
- Klon
- RB41914
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product FXN Primärantikörper
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anti-Frataxin (FXN) (AA 57-210) antibody
FXN Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal FXN-2124 unconjugated
anti-Frataxin (FXN) (AA 42-210) antibodyFXN Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Frataxin (FXN) (AA 72-102) antibodyFXN Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB12541 unconjugated
anti-Frataxin (FXN) (AA 143-172), (C-Term) antibodyFXN Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB12571 unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 1D9 unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 3G9 unconjugated
anti-Frataxin (FXN) (AA 41-207) antibodyFXN Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Frataxin (FXN) (AA 105-154) antibodyFXN Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Affe, Schwein, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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: "Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex." in: Biochemistry, Vol. 49, Issue 43, pp. 9132-9, (2010) (PubMed).
: "The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals." in: The Biochemical journal, Vol. 432, Issue 1, pp. 165-72, (2010) (PubMed).
: "Low predisposition to instability of the Friedreich ataxia gene in Cuban population." in: Clinical genetics, Vol. 77, Issue 6, pp. 598-600, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
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: "Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex." in: Biochemistry, Vol. 49, Issue 43, pp. 9132-9, (2010) (PubMed).
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- Target
- Frataxin (FXN)
- Andere Bezeichnung
- FXN (FXN Produkte)
- Hintergrund
- This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
- Molekulargewicht
- 23135
- NCBI Accession
- NP_000135, NP_001155178, NP_852090
- UniProt
- Q16595
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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