FGF8 Antikörper (N-Term)

Produktnummer ABIN1881345

Produktdetails anti-FGF8 Antikörper

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Bindungsspezifität: AA 30-59, N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Fgf8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of mouse Fgf8.

Klon: RB40263

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-FGF8 Antikörper (ABIN1881345)

Fleming, Quan, Wang, Amit, Rollins: "In vitro characterization of cardiac radiofrequency ablation lesions using optical coherence tomography." in: Optics express, Vol. 18, Issue 3, pp. 3079-92, (2010) (PubMed).

Yu, Poe, Schwarz, Elliot, Albertine, Fenton, Garg, Moon: "Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development." in: Developmental biology, Vol. 347, Issue 1, pp. 92-108, (2010) (PubMed).

Toyoda, Assimacopoulos, Wilcoxon, Taylor, Feldman, Suzuki-Hirano, Shimogori, Grove: "FGF8 acts as a classic diffusible morphogen to pattern the neocortex." in: Development (Cambridge, England), Vol. 137, Issue 20, pp. 3439-48, (2010) (PubMed).

Leung, Wong, Chan, Tam, Cheah: "Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 239, Issue 9, pp. 2319-29, (2010) (PubMed).

Mitsiadis, Graf, Luder, Gridley, Bluteau: "BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation." in: Development (Cambridge, England), Vol. 137, Issue 18, pp. 3025-35, (2010) (PubMed).

Details zu FGF8

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Andere Bezeichnung: Fgf8 (FGF8 Produkte)

Hintergrund: Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells. Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.

Molekulargewicht: 30420

NCBI Accession: NP_001159834, NP_001159835, NP_034335

UniProt: P37237

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Dopaminergic Neurogenesis