Cyclin B3 Antikörper (pThr280)

Produktnummer ABIN1881173

Der Kaninchen Polyklonal Anti-Cyclin B3-Antikörper wurde für DB validiert. Er ist geeignet, Cyclin B3 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für Cyclin B3 Antikörper (pThr280) (ABIN1881173)

Target: Cyclin B3 (CCNB3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin B3 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB42155

Produktdetails anti-Cyclin B3 Antikörper

Bindungsspezifität: pThr280

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCNB3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T280 of human CCNB3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Cyclin B3 Antikörper (ABIN1881173)

Cheng, Kapranov, Drenkow, Dike, Brubaker, Patel, Long, Stern, Tammana, Helt, Sementchenko, Piccolboni, Bekiranov, Bailey, Ganesh, Ghosh, Bell, Gerhard, Gingeras: "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution." in: Science (New York, N.Y.), Vol. 308, Issue 5725, pp. 1149-54, (2005) (PubMed).

Mouland, Coady, Yao, Cohen: "Hypophosphorylation of poly(A) polymerase and increased polyadenylation activity are associated with human immunodeficiency virus type 1 Vpr expression." in: Virology, Vol. 292, Issue 2, pp. 321-30, (2002) (PubMed).

Nguyen, Manova, Capodieci, Lindon, Bottega, Wang, Refik-Rogers, Pines, Wolgemuth, Koff: "Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41960-9, (2002) (PubMed).

Details zu Cyclin B3

Target: Cyclin B3 (CCNB3)

Andere Bezeichnung: CCNB3

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 157916

NCBI Accession: NP_149020, NP_391990

UniProt: Q8WWL7

Pathways: Zellzyklus, Chromatin Binding