LPAR3 Antikörper (C-Term)

Produktnummer ABIN187789

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LPAR3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für LPAR3 Antikörper (C-Term) (ABIN187789)

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LPAR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LPAR3 Antikörper

Bindungsspezifität: C-Term

Spezifität: Reacts with EDG-7. Species Reactivity: Human, other species not tested.

Sterilität: 0.2 μm filtered

Immunogen: Synthetic peptide derived from the C-terminal of the EDG-7 receptor.

Anwendungsinformationen

Applikationshinweise: Western Blot: Use at 5-10 µg/ml using a human EDG-7 receptor transfected cell line. The optimal dilution for a specific application should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Rabbit polyclonal antibody against human EDG-7 (CT). Available at 100 µg/100 µl in PBS with 0.08% sodium azide. Purification: Sterile filtered at 0.2 µm.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu LPAR3

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Andere Bezeichnung: EDG-7 / LPAR3

Hintergrund: EDG-7 belongs to a family of G-protein coupled receptors whose lignads are lysophospholipids. The ligand for EDG-7 sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-7 is expressed in prostate as well as other tissues.

Pathways: Regulation of Cell Size