LPAR1 Antikörper (C-Term)

Produktnummer ABIN187787

Produktdetails anti-LPAR1 Antikörper

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LPAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Reacts with EDG-2. Species Reactivity: Human and Rat. Other species not tested.

Sterilität: 0.2 μm filtered

Immunogen: KLH conjugated synthetic peptide corresponding to the AA 328-344 of human EDG-2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Rabbit polyclonal antibody against human endothelial cell differentiation gene 2 (CT). This antibody is provided as a 0.2 µm sterile-filtered solution in PBS with 0.08% sodium azide at a concentration of 1 mg/mL. Assayed to be >95% purity by SDS PAGE.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu LPAR1

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Andere Bezeichnung: EDG-2 / LPAR1 (LPAR1 Produkte)

Synonyme: EDG2 antikoerper, GPR26 antikoerper, Gpcr26 antikoerper, LPA1 antikoerper, Mrec1.3 antikoerper, VZG1 antikoerper, edg-2 antikoerper, rec.1.3 antikoerper, vzg-1 antikoerper, Edg2 antikoerper, EDG-2 antikoerper, 5031439C20 antikoerper, AI326300 antikoerper, Kdt2 antikoerper, lpA1 antikoerper, edg2 antikoerper, si:dz22b13.1 antikoerper, si:dz46m7.1 antikoerper, zgc:92157 antikoerper, LPA receptor 1-A antikoerper, LPA-1-A antikoerper, gpr26 antikoerper, lpa1 antikoerper, lpa1r antikoerper, lpa1r1 antikoerper, lpar1 antikoerper, lpar1-a antikoerper, lpar1-b antikoerper, vzg1 antikoerper, xLPA1-1 antikoerper, LPA receptor 1-B antikoerper, LPA-1-B antikoerper, edg2-A antikoerper, xLPA1-2 antikoerper, xlpa1R antikoerper, lysophosphatidic acid receptor 1 antikoerper, lysophosphatidic acid receptor 1 S homeolog antikoerper, lysophosphatidic acid receptor 1 L homeolog antikoerper, LPAR1 antikoerper, Lpar1 antikoerper, lpar1 antikoerper, lpar1.S antikoerper, lpar1.L antikoerper

Hintergrund: Endothelial cell differentiation gene-2 (EDG-2) receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG-2, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduction decreases in c[AMP]i through Gi and increases in [Ca+2]i by augmenting phospholipase C through Gq/11 and beta/gamma dimers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG-2 is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG-2 receptors (with EDG-4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration