Clusterin Antikörper

Produktnummer ABIN187541

Der Maus Monoklonal Anti-Clusterin Antikörper wurde für WB, IP, IF und IHC (fro) validiert. Er ist geeignet, Clusterin in Proben von Human zu detektieren.

Kurzübersicht für Clusterin Antikörper (ABIN187541)

Target: Clusterin (CLU)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Clusterin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: CLI-9

Produktdetails anti-Clusterin Antikörper

Spezifität: Recognizes human clusterin. Species Reactivity: Human. Others not tested.

Reinheit: 95 % as determined by SDS-PAGE.

Immunogen: Purified human clusterin (TRPM-2).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: Frozen sections. Immunoprecipitation Immunocytochemistry Western blot: Use at approximately a 1:2,000 dilution. The optimal dilution for a specific application should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 µg of liquid purified monoclonal antibody at 1 mg/mL in PBS containing 0.02% sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu Clusterin

Target: Clusterin (CLU)

Andere Bezeichnung: Apolipoprotein J (Clusterin)

Hintergrund: Clusterin is the first identified extracellular mammalian chaperone and appears to be implicated in such diverse processes as sperm maturation, regulation of complement activation, programmed cell death, tissue remodeling and lipid transport. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin gene expression as a prominent marker of apoptotic cell loss. A dual role has been shown for clusterin in that cells can be protected from damage and dead cells can be more easily removed after some types of cellular damage.

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling