ABCA1 Antikörper

Produktnummer ABIN187475

Produktdetails anti-ABCA1 Antikörper

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ABCA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität: Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder resulting from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. Species Human. Other species not tested.

Immunogen: Peptide corresponding to amino acids 1800-2260.

Klon: AB1-G6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry Western blot ELISA Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 µg of antibody at 1 mg/mL in PBS, pH 7.4, with 0.5% sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ABCA1

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Andere Bezeichnung: ABCA1 (ABCA1 Produkte)

Synonyme: ABC-1 antikoerper, ABC1 antikoerper, CERP antikoerper, HDLDT1 antikoerper, TGD antikoerper, ABCA1 antikoerper, Abc1 antikoerper, ATP-binding cassette A1 antikoerper, Arabidopsis thaliana ATP-binding cassette A1 antikoerper, AtABCA1 antikoerper, im:7136239 antikoerper, sb:cb407 antikoerper, wu:fa07e06 antikoerper, zgc:171581 antikoerper, ATP binding cassette subfamily A member 1 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 1 antikoerper, ATP-binding cassette A1 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 1B antikoerper, ABCA1 antikoerper, Abca1 antikoerper, abca1 antikoerper, abca1b antikoerper

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism