FAS Antikörper (FITC)

Produktnummer ABIN187286

Der Maus Monoklonal Anti-FAS Antikörper wurde für FACS validiert. Er ist geeignet, FAS in Proben von Human zu detektieren.

Kurzübersicht für FAS Antikörper (FITC) (ABIN187286)

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FAS Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: 3-22

Produktdetails anti-FAS Antikörper (FITC)

Spezifität: Species Reactivity: Human. Others not tested.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Monitoring of activated T cells in peripheral blood, Analysis of NK subsets, Study of B cell activation. Flow cytometry Immunofluorescence PBMC: Add 10 µL of mAb/106 PBMC in 100 µL PBS. Mix gently and incubate for 15 minutes at 4 °C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. Whole Blood: Add 10 µL of mAb/100 µL of whole blood. Mix gently and incubate for 15 minutes at room temperature (RT). Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturer's instructions for lysed whole blood and immunofluorescence analysis with a flow cytometer or microscope. The optimal dilution for a specific application should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1.0 mL of FITC-labeled monoclonal antibody in PBS, 0.08% sodium azide and protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Andere Bezeichnung: CD95 / FAS

Hintergrund: Activation of either the 55 kDa tumor necrosis factor receptor (TNF-R1) or CD95 (Fas/Apo-1) causes apoptosis of cells and liver failure in mice, and has been associated with human liver disorders.

Pathways: p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity