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FAS Antikörper (FITC)

FAS Reaktivität: Human FACS Wirt: Maus Monoclonal 3-22 FITC

Produktnummer ABIN187286

Datenblatt (PDF)

Target Alle FAS Antikörper anzeigen

FAS (TNF Receptor Superfamily, Member 6 (FAS))
Reaktivität
225

62

62

19

8

7

4

4

3

3

2

1

1

1
Human
Wirt
157

101

4

3

2

1

1

1
Maus
Passende Sekundärantikörper
Klonalität
155

113

1
Monoklonal
Konjugat
120

28

26

13

12

7

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser FAS Antikörper ist konjugiert mit FITC
Applikation
158

129

72

58

39

34

30

26

26

19

16

11

8

5

5

4

4

2

2

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Spezifität

Species Reactivity: Human. Others not tested.

Klon

3-22

Isotyp

IgG1

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Applikationshinweise

Monitoring of activated T cells in peripheral blood, Analysis of NK subsets, Study of B cell activation. Flow cytometry Immunofluorescence PBMC: Add 10 µL of mAb/106 PBMC in 100 µL PBS. Mix gently and incubate for 15 minutes at 4 °C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. Whole Blood: Add 10 µL of mAb/100 µL of whole blood. Mix gently and incubate for 15 minutes at room temperature (RT). Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturer's instructions for lysed whole blood and immunofluorescence analysis with a flow cytometer or microscope. The optimal dilution for a specific application should be determined by the researcher.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

1.0 mL of FITC-labeled monoclonal antibody in PBS, 0.08% sodium azide and protein stabilizer.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C
Target

FAS (TNF Receptor Superfamily, Member 6 (FAS))

Andere Bezeichnung

CD95 / FAS (FAS Produkte)

Hintergrund

Activation of either the 55 kDa tumor necrosis factor receptor (TNF-R1) or CD95 (Fas/Apo-1) causes apoptosis of cells and liver failure in mice, and has been associated with human liver disorders.

Pathways

p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity