TSC1 Antikörper (C-Term)

Produktnummer ABIN185619

Dieses Anti-TSC1-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von TSC1 in ELISA, WB und IHC. Geeignet für Human.

Kurzübersicht für TSC1 Antikörper (C-Term) (ABIN185619)

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TSC1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Güteklasse: Verified

Produktdetails anti-TSC1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Hamartin / TSC1 (isoform 1)

Sequenz: QLHIMDYNET HHEH

Spezifität: This antibody is expected to recognise isoform 1 (NP_000359.1) only.

Kreuzreaktivität: Hund, Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-QLHIMDYNETHHEH, from the C Terminus of the protein sequence according to NP_000359.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Uterus and Liver. Recommended concentration: 3.75 μg/mL.

Western Blot: Approx 150 kDa band observed in Human Brain lysates (calculated MW of 130 kDa according to NP_000359.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Miloloza et al Hum Mol Genet. 2000

Peptide ELISA: antibody detection limit dilution 1:128000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu TSC1

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Andere Bezeichnung: TSC1

Hintergrund: TSC1, hamartin, tuberous sclerosis 1 , HGNC:12362, KIAA0243, LAM, MGC86987, TSC, tuberous sclerosis 1 protein, tumor suppressor

Gen-ID: 7248, 64930

NCBI Accession: NP_000359

Pathways: RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation