GSTM1 Antikörper (C-Term)

Produktnummer ABIN185334

Dieses Anti-GSTM1-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von GSTM1 in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für GSTM1 Antikörper (C-Term) (ABIN185334)

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GSTM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Verified

Produktdetails anti-GSTM1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: GSTM1 / GSTM2

Sequenz: CVFSKMAVWG NK

Spezifität: This antibody is expected to recognise both reported variants of human GSTM1 protein (NP_000552.2, NP_666533.1) and wil also recognise human GSTM2 protein (NP_000839.1).

Kreuzreaktivität: Human

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence CVFSKMAVWGNK, from the C Terminus of the protein sequence according to NP_000552.2, NP_666533.1, NP_000839.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western Blot: Approx 26 kDa band observed in Human Liver and Human Lung lysates (calculated MW of 25.7 kDa according to NP_000552.2, and NP_000839.1). Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-GSTM1 Antikörper (ABIN185334)

Endo, Uno, Seki, Ariga, Kusumi, Mitsumata, Yamada, Makishima: "Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene." in: Toxicology and applied pharmacology, Vol. 230, Issue 2, pp. 135-43, (2008) (PubMed).

Details zu GSTM1

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Andere Bezeichnung: GSTM1 / GSTM2

Hintergrund: GSTM1, GSTM2, MU, H-B, GST1, GTH4, GTM1, MU-1, GSTM1-1, MGC26563, GSTM1a-1a, GSTM1b-1b, glutathione S-transferase M1, HB subunit 4, GST class-mu 1, glutathione S-aryltransferase, glutathione S-alkyltransferase, glutathione S-transferase, Mu-1, glutathione

Gen-ID: 2944, 2946

NCBI Accession: NP_000552, NP_666533, NP_000839

Pathways: Negative Regulation of Transporter Activity