BIM Antikörper (C-Term)

Produktnummer ABIN185253

Dieses Anti-BIM-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von BIM in WB und ELISA. Geeignet für Human.

Kurzübersicht für BIM Antikörper (C-Term) (ABIN185253)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser BIM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Verified

Produktdetails anti-BIM Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BIM

Sequenz: FNAYYARRLE K

Spezifität: This antibody is expected to recognise at least reported isoforms Bim-alpha1 (BimABCD), Bim-alpha2 (BimACD) and Bim-alpha3 (BimAD).

Kreuzreaktivität: Human

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-FNAYYARRLEK, from the C Terminus of the protein sequence according to NP_619528.1, NP_619529.1, NP_996886.1,.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western Blot: Approx 23 kDa band observed in lysates of cell line K562 (calculated MW of 18.5 kDa according to NP_619528.1). Recommended for use at 0.5-2 μg/mL. Primary incubated 1 hour at room temperature.

Peptide ELISA: antibody detection limit dilution 1:16000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Andere Bezeichnung: BCL2L11

Hintergrund: BCL2L11, BCL2-like 11 (apoptosis facilitator), BAM, BIM, BOD, bcl-2 interacting mediator of cell death, bcl-2 interacting protein Bim, bcl-2-like protein 11, bcl-2-related ovarian death agonist, bcl2-L-11, Bim-alpha1, Bim-alpha2, Bim-alpha3

Gen-ID: 10018

NCBI Accession: NP_619528, NP_619529, NP_996886

Pathways: PI3K-Akt Signalweg, Neurotrophin Signalübertragung, Tube Formation, Positive Regulation of Endopeptidase Activity