STXBP1 Antikörper (C-Term)

Produktnummer ABIN185107

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch STXBP1 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für STXBP1 Antikörper (C-Term) (ABIN185107)

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser STXBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Güteklasse: Verified

Produktdetails anti-STXBP1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: MUNC18 / STXBP1 (isoform a)

Sequenz: SRVSFEDQAP TME

Spezifität: This antibody is expected to recognize isoform a (NP_003156.1).

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-SRVSFEDQAPTME, from the C Terminus of the protein sequence according to NP_003156.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Brain (Cortex). Recommended concentration: 5 μg/mL.

Western Blot: Approx 70-75 kDa band observed in Human Cerebellum lysates (calculated MW of 68.7 kDa according to Human NP_003156.1). Recommended concentration: 0.1-0.3 μg/mL. Primary incubation 1 hour at room temperature.

Peptide ELISA: antibody detection limit dilution 1:16000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-STXBP1 Antikörper (ABIN185107)

Meijer, Cijsouw, Toonen, Verhage: "Synaptic Effects of Munc18-1 Alternative Splicing in Excitatory Hippocampal Neurons." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138950, (2016) (PubMed).

Details zu STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Andere Bezeichnung: STXBP1

Hintergrund: STXBP1, MUNC18-1, UNC18, hUNC18, syntaxin binding protein 1, Hunc18, rbSec1, syntaxin-binding protein 1, RP11-56D16.3, EIEE4, FLJ37475, RBSEC1

Gen-ID: 6812, 20910

NCBI Accession: NP_003156

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport