FOXL2 Antikörper (C-Term)

Produktnummer ABIN185040

Dieses Anti-FOXL2-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von FOXL2 in WB, ELISA und IHC. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für FOXL2 Antikörper (C-Term) (ABIN185040)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FOXL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Güteklasse: Verified

Produktdetails anti-FOXL2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FOXL2 / BPES

Sequenz: DSKTGALHSR LDL

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-DSKTGALHSRLDL, from the C Terminus of the protein sequence according to NP_075555.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Ovary. Recommended concentration: 8 μg/mL.

Western Blot: Approx. 50 kDa band observed in Mouse Ovary lysates and in preliminary testing of Human Uterus and Rat Ovary lysate (calculated MW of 38.9 kDa according to Mouse NP_036150.1). This molecular weight is routinely observed by other sources. Reco

Peptide ELISA: antibody detection limit dilution 1:128000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-FOXL2 Antikörper (ABIN185040)

Padua, Fox, Jiang, Morse, Tevosian: "Simultaneous gene deletion of gata4 and gata6 leads to early disruption of follicular development and germ cell loss in the murine ovary." in: Biology of reproduction, Vol. 91, Issue 1, pp. 24, (2014) (PubMed).

Blount, Schmidt, Justice, Vale, Fischer, Bilezikjian: "FoxL2 and Smad3 coordinately regulate follistatin gene transcription." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7631-45, (2009) (PubMed).

Details zu FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Andere Bezeichnung: FOXL2

Hintergrund: FOXL2, BPES, forkhead box L2, PFRK, BPES1, PINTO, forkhead transcription factor FOXL2, blepharophimosis, epicanthus inversus and ptosis, Blepharophimosis, epicanthus inversus, and ptosis 1, POF3

Gen-ID: 668, 26927

NCBI Accession: NP_075555

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity