NLRP3 Antikörper (C-Term)

Produktnummer ABIN184887

Dieses Anti-NLRP3-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von NLRP3 in ELISA, IHC, IF und FACS. Geeignet für Human.

Kurzübersicht für NLRP3 Antikörper (C-Term) (ABIN184887)

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NLRP3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Verified

Produktdetails anti-NLRP3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CIAS1 / cryopyrin ( C Terminus)

Sequenz: EKPELTVVFE PSW

Spezifität: Variants (NP_001073289.1, NP_004886.3) encode the same isoform.

Kreuzreaktivität: Rind (Kuh), Human, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-EKPELTVVFEPSW, from the C Terminus of the protein sequence according to NP_001073289.1, NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Colon. Recommended concentration: 4 μg/mL.

Western Blot: This antibody is not recommended for use in Western blotting.

Peptide ELISA: antibody detection limit dilution 1:128000.

Kommentare:

Immunofluorescence: Expression of the protein seen in the cytoplasm and plasma membrane of U937 cells. Recommended concentration: 10μg/ml.

Flow Cytometry: Flow cytometric analysis of U937 cells. Recommended concentra

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu NLRP3

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Andere Bezeichnung: NLRP3

Hintergrund: NLRP3, CIAS1, FCU, MWS, FCAS, NALP3, C1orf7, PYPAF1, AII/AVP, AGTAVPRL, CRYOPYRIN, cold autoinflammatory syndrome 1, cryopyrin, Muckle-Wells syndrome, chromosome 1 open reading frame 7, PYRIN-containing APAF1-like protein 1, neuronal apoptosis inhibitor p

Gen-ID: 114548

NCBI Accession: NP_001073289, NP_004886, NP_899632, NP_001120933, NP_001120934

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome