Cadherin 5 Antikörper (AA 29-223)

Produktnummer ABIN1846316

Der Maus Monoklonal Anti-Cadherin 5-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, Cadherin 5 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Cadherin 5 Antikörper (AA 29-223) (ABIN1846316)

Target: Cadherin 5 (CDH5)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-Cadherin 5 Antikörper

Bindungsspezifität: AA 29-223

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CDH5 (AA: 29-223) expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: CDH5

Hintergrund: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.An alternative splice variant has been described but its full length sequence has not been determined.

Molekulargewicht: 87.5 kDa

Gen-ID: 1003, 307618

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2