Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target
KLF1
(Kruppel-Like Factor 1 (erythroid) (KLF1))
Andere Bezeichnung
KLF1
Hintergrund
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes.The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter.Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype.