CD59 Antikörper (AA 31-111)
Kurzübersicht für CD59 Antikörper (AA 31-111) (ABIN1845905)
Target
Alle CD59 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 31-111
- 
                                            Aufreinigung
- Purified antibody
- 
                                            Immunogen
- Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli.
- 
                                            Isotyp
- IgG1
 
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- 
    - 
                                            Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1.0 mg/mL
- 
                                            Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
 
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- 
    - CD59
- 
                                            Andere Bezeichnung
- CD59
- 
                                            Hintergrund
- This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.
- 
                                            Molekulargewicht
- 14.2 kDa
- 
                                            Gen-ID
- 966
- 
                                            UniProt
- P13987
- 
                                            Pathways
- Komplementsystem
 Target
- 
                    
 
                                     
                                     
                                    