CD31 Antikörper (FITC)

Produktnummer ABIN182060

Der Maus Monoklonal Anti-CD31 Antikörper wurde für FACS validiert. Er ist geeignet, CD31 in Proben von Rind (Kuh) und Schaf zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für CD31 Antikörper (FITC) (ABIN182060)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reaktivität: Rind (Kuh), Schaf

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD31 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: CO-3E1D4

Produktdetails anti-CD31 Antikörper (FITC)

Kreuzreaktivität (Details): Species reactivity (tested):Sheep. Reacts with Bovine and Goat.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Ovine leucocytes. Spleen cells from immunised BALB/c mice were fused with cells of the SP2- 0/Ag14 mouse myeloma cell line

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-CD31 Antikörper (FITC) (ABIN182060)

Rocheleau, Khader, Ngo, Boehnlein, McDavitt, Lattimore, Recht, McCarty, Haley: "Pilot study of novel lab methodology and testing of platelet function in adolescent women with heavy menstrual bleeding." in: Pediatric research, Vol. 83, Issue 3, pp. 693-701, (2018) (PubMed).

Details zu CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung: CD31 / PECAM1

Hintergrund: CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). Ovine CD31 is predominantly expressed by peripheral blood platelets and a small percentage of lymphocytes. CD31 is also highly expressed by ovine endothelial cells.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule

UniProt: P51866

Pathways: Regulation of Actin Filament Polymerization