TREM2 Antikörper

Produktnummer ABIN1820125

Dieser Ratte Monoklonal Antikörper detektiert spezifisch TREM2 in FACS und Func. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für TREM2 Antikörper (ABIN1820125)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TREM2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: 78-18

Produktdetails anti-TREM2 Antikörper

Spezifität: Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.

Aufreinigung: Protein G purified

Endotoxin-Niveau: Low Endotoxin

Immunogen: Mouse TREM-2 Fc fusion protein.

Type of Immunogen: Fusion protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:25 - 1:200), Func

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Andere Bezeichnung: TREM2 / TREM-2

Hintergrund: Name/Gene ID: TREM2

Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c

Gen-ID: 54209