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CD86 Antikörper

CD86 Reaktivität: Ratte FACS, IP, IHC, IHC (fro) Wirt: Maus Monoclonal 24F unconjugated

Produktnummer ABIN1819941

Datenblatt (PDF)

Target Alle CD86 Antikörper anzeigen

CD86
Reaktivität
146

117

56

19

10

9

6

4

4

3

2
Ratte
Wirt
88

76

71
Maus
Passende Sekundärantikörper
Klonalität
173

58

2
Monoklonal
Konjugat
83

25

20

17

11

8

7

7

5

4

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD86 Antikörper ist unkonjugiert
Applikation
167

92

51

42

38

34

32

25

18

16

14

13

13

10

8

7

5

4

3

3

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität

Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.

Aufreinigung

Protein G purified

Immunogen

HTLV-1 transformed Lewis-S1 cells.

Type of Immunogen: Cells

Klon

24F

Isotyp

IgG1

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CD86 Reaktivität: Human, Maus, Ratte FACS, WB, IHC, IF, ELISA, BP, StM, Coat Wirt: Kaninchen Monoclonal C86-2160R unconjugated Recombinant Antibody

anti-CD86 (CD86) (AA 30-247) antibody
CD86 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD86 (CD86) antibody
CD86 Reaktivität: Human FACS, WB, IP, IHC (fro), Func Wirt: Maus Monoclonal BU63 unconjugated

anti-CD86 (CD86) antibody (FITC)
CD86 Reaktivität: Maus FACS Wirt: Ratte Monoclonal GL-1 FITC

anti-CD86 (CD86) antibody (PerCP)
CD86 Reaktivität: Human FACS Wirt: Maus Monoclonal BU63 PerCP

Applikationshinweise

Approved: Flo (1:25 - 1:200), IHC, IHC-Fr, IP

Kommentare

Target Species of Antibody: Rat

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS, 0.09 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

4°C or -20°C, Avoid freeze-thaw cycles.
Target

CD86

Andere Bezeichnung

CD86 (CD86 Produkte)

Hintergrund

Name/Gene ID: CD86

Synonyms: CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 Molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2

Gen-ID

942

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation