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CD86 Antikörper (FITC)

CD86 Reaktivität: Ratte FACS Wirt: Maus Monoclonal 24F FITC

Produktnummer ABIN1819940

Datenblatt (PDF)

Target Alle CD86 Antikörper anzeigen

CD86
Reaktivität
149

119

56

19

10

9

6

4

4

3

2
Ratte
Wirt
90

78

72
Maus
Passende Sekundärantikörper
Klonalität
176

60

2
Monoklonal
Konjugat
88

25

20

17

11

8

7

7

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD86 Antikörper ist konjugiert mit FITC
Applikation
170

94

51

44

38

36

32

25

18

16

14

13

13

10

8

7

5

4

3

3

2

2

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86.

Aufreinigung

Protein G purified

Immunogen

HTLV-1 transformed Lewis-S1 cells.

Type of Immunogen: Cells

Klon

24F

Isotyp

IgG1

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CD86 Reaktivität: Human, Maus, Ratte FACS, WB, IHC, ELISA, IF, BP, StM, Coat Wirt: Kaninchen Monoclonal C86-2160R unconjugated Recombinant Antibody

anti-CD86 (CD86) (AA 30-247) antibody
CD86 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

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CD86 Reaktivität: Human FACS, WB, IP, IHC (fro), Func Wirt: Maus Monoclonal BU63 unconjugated

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CD86 Reaktivität: Maus FACS Wirt: Ratte Monoclonal GL-1 FITC

anti-CD86 (CD86) antibody (PerCP)
CD86 Reaktivität: Human FACS Wirt: Maus Monoclonal BU63 PerCP

Applikationshinweise

Approved: Flo (1:1 - 1:10)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare

Target Species of Antibody: Rat

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS, 0.09 % sodium azide, 1 % BSA

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing. Protect from light.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
Target

CD86

Andere Bezeichnung

CD86 (CD86 Produkte)

Hintergrund

Name/Gene ID: CD86

Synonyms: CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 Molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2

Gen-ID

942

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation