LAMP2 Antikörper (FITC)
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- Target Alle LAMP2 Antikörper anzeigen
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
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Reaktivität
- Human, Hund, Nerz
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LAMP2 Antikörper ist konjugiert mit FITC
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)
- Spezifität
- Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.
- Keine Kreuzreaktivität
- Maus, Ratte (Rattus)
- Aufreinigung
- Protein G purified
- Immunogen
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MDCK (Madin-Darby Canine Kidney) cells.
Type of Immunogen: Cells - Klon
- AC17
- Isotyp
- IgG1
- Top Product
- Discover our top product LAMP2 Primärantikörper
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- Applikationshinweise
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Approved: Flo (1:1), IF, IP, WB
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Kommentare
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Target Species of Antibody: Dog
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide, 1 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing. Protect from light.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- Target
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Andere Bezeichnung
- LAMP2 / CD107b (LAMP2 Produkte)
- Synonyme
- CD107b antikoerper, LAMP-2 antikoerper, LAMPB antikoerper, LGP110 antikoerper, Lamp-2 antikoerper, Lamp-2a antikoerper, Lamp-2b antikoerper, Lamp-2c antikoerper, Mac3 antikoerper, cd107b antikoerper, lamp-2 antikoerper, lampb antikoerper, LAMP2 antikoerper, lamp2 antikoerper, DKFZp459J126 antikoerper, LGP-B antikoerper, sb:cb587 antikoerper, wu:fb14a06 antikoerper, zgc:103532 antikoerper, lysosomal associated membrane protein 2 antikoerper, lysosomal-associated membrane protein 2 antikoerper, lysosomal-associated membrane protein 2 S homeolog antikoerper, lysosomal membrane glycoprotein 2 antikoerper, LAMP2 antikoerper, Lamp2 antikoerper, lamp2.S antikoerper, lamp2 antikoerper
- Hintergrund
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Name/Gene ID: LAMP2
Family: Cancer
Synonyms: LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2 - Gen-ID
- 3920
- Pathways
- Autophagie
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