CD47 Antikörper

Produktnummer ABIN6796388

Der Maus-Monoklonal Anti-CD47-Antikörper wurde für FACS, IHC, IP und IHC (fro) validiert. Er ist geeignet zum Nachweis von CD47 in Proben aus Human. }

Kurzübersicht für CD47 Antikörper (ABIN6796388)

Target: CD47

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD47 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 1-1A4

Produktdetails anti-CD47 Antikörper

Spezifität: Specific for human CD47, also known as integrin-associated protein, a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells.

Aufreinigung: Protein G purified

Immunogen: Human erythrocytes.

Type of Immunogen: Cells

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:25 - 1:100), IHC, IHC-Fr, IP

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu CD47

Target: CD47

Andere Bezeichnung: CD47

Hintergrund: Name/Gene ID: CD47

Synonyms: CD47, CD47 antigen, CD47 Molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP

Gen-ID: 961