CD47 Antikörper
Kurzübersicht für CD47 Antikörper (ABIN6796388)
Target
Alle CD47 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Specific for human CD47, also known as integrin-associated protein, a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells.
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Aufreinigung
- Protein G purified
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Immunogen
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Human erythrocytes.
Type of Immunogen: Cells -
Isotyp
- IgG2b
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Applikationshinweise
- Approved: Flo (1:25 - 1:100), IHC, IHC-Fr, IP
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- CD47
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Andere Bezeichnung
- CD47
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Hintergrund
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Name/Gene ID: CD47
Synonyms: CD47, CD47 antigen, CD47 Molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP -
Gen-ID
- 961
Target
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