SLA Class II DR Antikörper (FITC)

Produktnummer ABIN1819798

Produktdetails

Target: SLA Class II DR

Reaktivität: Schwein, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: FITC

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Spezifität: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR. The antibody is specific for SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells. This clone reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of porcine SLA DR. Immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labeled porcine peripheral blood mononuclear cells. Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and Staphylococcal enterotoxin B.

Aufreinigung: Protein G purified

Immunogen: Porcine monocytes.

Klon: 2E9-13

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1), IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. For Flow cytometry it is suggested to use 10 μL of neat antibody with 1 x 10⁶ cells in 100 μL.

Kommentare:

Target Species of Antibody: Pig

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Protect from light.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Antigendetails

Target: SLA Class II DR