SLA Class II DR Antikörper

Produktnummer ABIN1819096

Dieser Maus Monoklonal Antikörper detektiert spezifisch SLA Class II DR in FACS, IHC (fro), IP und IHC. Es zeigt Reaktivität gegenüber Proben von Schwein und Rind (Kuh).

Kurzübersicht für SLA Class II DR Antikörper (ABIN1819096)

Target: SLA Class II DR

Reaktivität: Schwein, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Klon: 2E9-13

Produktdetails

Spezifität: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR. Clone 2E9/13 is specific for SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells. This clone reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of porcine SLA DR. Immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labeled porcine peripheral blood mononuclear cells. Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and Staphylococcal enterotoxin B, see for details.

Aufreinigung: Protein G purified

Immunogen: Porcine monocytes.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Pig

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Antigendetails

Target: SLA Class II DR