CD31 Antikörper (PE)
Kurzübersicht für CD31 Antikörper (PE) (ABIN181960)
Target
Alle CD31 (PECAM1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Affinity Chromatography.
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Immunogen
- Porcine CD31/human IgGFc fusion protein
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Isotyp
- IgG1
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Applikationshinweise
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Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL or 100 μL of lysed whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with 0.25 mL distilled water.
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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Andere Bezeichnung
- CD31 / PECAM1
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Hintergrund
- Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms' tumors, Ewing's sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2α1 and B2αM Integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66 % of patients with Kallmann's syndrome, anosmia with secondary hypogonadism.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
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Gen-ID
- 9606
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UniProt
- P16284
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Pathways
- Regulation of Actin Filament Polymerization
Target
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