TREM2 Antikörper (PE)

Produktnummer ABIN1819128

Produktdetails anti-TREM2 Antikörper (PE)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TREM2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.

Aufreinigung: Protein G purified

Immunogen: Mouse TREM-2 Fc fusion protein.

Type of Immunogen: Fusion protein

Klon: 78-18

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: 1 mL sterile distilled water

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze. Protect from light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze. Protect from light.

Details zu TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Andere Bezeichnung: TREM2 / TREM-2 (TREM2 Produkte)

Hintergrund: Name/Gene ID: TREM2

Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c

Gen-ID: 54209