GM-CSF Antikörper

Produktnummer ABIN181873

Dieser Maus Monoklonal Antikörper detektiert spezifisch GM-CSF in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Schaf.

Kurzübersicht für GM-CSF Antikörper (ABIN181873)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Schaf

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GM-CSF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 3C2

Produktdetails anti-GM-CSF Antikörper

Spezifität: This antibody recognises recombinant and native GM-CSF. Clone 8D8 has been reported to neutralise the activity of both recombinant and native GM-CSF.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: CHO expressed recombinant ovine GM-CSF. Spleen cells from immunised Balb/c mice were fused with cells of the NSO myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot. ELISA: 1/100 as detecting antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: GM-CSF

Hintergrund: The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim

Gen-ID: 443400

NCBI Accession: NP_001009805

UniProt: P28773

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin