Macrophage Scavenger Receptor 1 Antikörper (PE)

Produktnummer ABIN181781

Der Ratte Monoklonal Anti-Macrophage Scavenger Receptor 1-Antikörper wurde für FACS validiert. Er ist geeignet, Macrophage Scavenger Receptor 1 in Proben von Maus zu detektieren.

Kurzübersicht für Macrophage Scavenger Receptor 1 Antikörper (PE) (ABIN181781)

Target: Macrophage Scavenger Receptor 1 (MSR1)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Macrophage Scavenger Receptor 1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 2F8

Produktdetails anti-Macrophage Scavenger Receptor 1 Antikörper (PE)

Spezifität: This antibody recognises the murine scavenger receptor class A (SRA), type I and II, also known as CD204. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. Recent research shows that clone 2F8 recognises an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: RAW264 cell line. Spleen cells from immunised AO rats were fused with cells of the Y3 rat myeloma cell line.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL distilled water.

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Macrophage Scavenger Receptor 1

Target: Macrophage Scavenger Receptor 1 (MSR1)

Andere Bezeichnung: CD204

Hintergrund: CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions.Synonyms: MSR1, Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor types I and II, SCARA1, Scavenger receptor class A member 1

Gen-ID: 20288

NCBI Accession: NP_001106797

UniProt: P30204