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Macrophage Scavenger Receptor 1 Antikörper

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch Macrophage Scavenger Receptor 1 in WB, FACS, IP, IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Maus und Schwein.
Produktnummer ABIN181780

Kurzübersicht für Macrophage Scavenger Receptor 1 Antikörper (ABIN181780)

Target

Alle Macrophage Scavenger Receptor 1 (MSR1) Antikörper anzeigen
Macrophage Scavenger Receptor 1 (MSR1)

Reaktivität

  • 63
  • 61
  • 16
  • 16
  • 12
  • 11
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Maus, Schwein

Wirt

  • 61
  • 21
  • 6
Ratte

Klonalität

  • 58
  • 25
  • 1
Monoklonal

Konjugat

  • 41
  • 8
  • 7
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Macrophage Scavenger Receptor 1 Antikörper ist unkonjugiert

Applikation

  • 66
  • 40
  • 32
  • 19
  • 15
  • 13
  • 13
  • 13
  • 7
  • 7
  • 5
  • 5
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon

2F8
  • Spezifität

    This antibody recognizes the Murine scavenger receptor class A (SRA), type I and II, also known as CD204. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. We recommend the use of SM029LE for this purpose. Recent research shows that clone 2F8 recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 Mouse strain.

    Aufreinigung

    Affinity Chromatography on Protein G

    Immunogen

    Raw 264 cell line. Remarks: Spleen cells from immunised AO rats were fused with cells of the Y3 rat myeloma cell line.

    Isotyp

    IgG2b
  • Applikationshinweise

    ELISA. Western Blot. Immunoprecipitation. Immunohistochemistry on frozen sections. Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, 0.09 % Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Macrophage Scavenger Receptor 1 (MSR1)

    Andere Bezeichnung

    CD204

    Hintergrund

    CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions.Synonyms: MSR1, Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor types I and II, SCARA1, Scavenger receptor class A member 1

    Gen-ID

    20288

    NCBI Accession

    NP_001106797

    UniProt

    P30204
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