Transferrin Receptor Antikörper

Produktnummer ABIN181740

Der Ratte Monoklonal anti-Transferrin Receptor Antikörper (Klon ER-MP21) (ABIN181740) detektiert spezifisch Transferrin Receptor in FACS, IP und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Transferrin Receptor Antikörper (ABIN181740)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Klon: ER-MP21

Produktdetails anti-Transferrin Receptor Antikörper

Spezifität: This antibody recognises murine CD71, a 200 kDa antigen which is otherwise known as transferrin receptor.

Aufreinigung: Affinity chromatography on Protein G

Endotoxin-Niveau: Low Endotoxin

Immunogen: Balb/c macrophage precursor cell hybrids. Cells from immunised rats were fused with cells of the rat Y3-Ag1.2.3 myeloma cell line.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Functional Assays. Flow Cytometry: 1/50 - 1/100, use 10 μL of the suggested working dilution to label 10^6 cellsin 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71 / TFRC

Hintergrund: CD71 is expressed by all proliferating cell populations and exists as a homodimer at the cell surface. Clone ER-MP21 inhibits iron uptake and cell proliferation but does not compete with transferrin for binding to its receptor, which suggests that clone ER-MP21 binds to an epitope that is different from the transferrin-binding site.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gen-ID: 22042

NCBI Accession: NP_035768

UniProt: Q62351

Pathways: Transition Metal Ion Homeostasis