CCL19 Antikörper

Produktnummer ABIN181150

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CCL19 in EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CCL19 Antikörper (ABIN181150)

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCL19 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Produktdetails anti-CCL19 Antikörper

Spezifität: This antibody detects MIP-3 beta.

Produktmerkmale: Synonyms: C-C motif chemokine 19, CCL-19, ELC, MIP3B, MIP-3 beta, Small-inducible cytokine A19,SCYA19, Exodus-3, Small-inducible cytokine A19, EBI1-ligand chemokine, Beta chemokineexodus-3, CK beta-11, Macrophage inflammatory protein 3 beta

Aufreinigung: Protein A chromatography

Immunogen: Recombinant human MIP-3-beta

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: In a sandwich ELISA (assuming 100 l/well), a concentration of 2-3 μg/mL of thisantibody will detect at least 0.2 ng/well of recombinant human MIP-3-beta when used withbiotinylated antigen affinity purified anti-human MIP-3-beta as the detection antibody at aconcentration of at least 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 1 mg/mL.

Konservierungsmittel: Azide free

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2 - 8 °C for six weeks. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CCL19

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Andere Bezeichnung: MIP3-beta / CCL19

Hintergrund: MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30 % aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the anti-inflammatory cytokine IL10. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphocytes, dendritic cells, human T lymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13.Synonyms: Beta chemokine exodus-3, C-C motif chemokine 19, CCL-19, CK beta-11, EBI1-ligand chemokine, ELC, Exodus-3, MIP-3 beta, MIP3B, Macrophage inflammatory protein 3 beta, SCYA19, Small-inducible cytokine A19, Small-inducible cytokine A19

Gen-ID: 6363

UniProt: Q99731

Pathways: Positive Regulation of Immune Effector Process