C4BPA Antikörper

Produktnummer ABIN181109

Der Maus Monoklonal Anti-C4BPA-Antikörper wurde für IHC (p) und EIA validiert. Er ist geeignet, C4BPA in Proben von Human zu detektieren.

Kurzübersicht für C4BPA Antikörper (ABIN181109)

Target: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C4BPA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 10-07-14

Produktdetails anti-C4BPA Antikörper

Spezifität: This antibody recognizes complement component 4 binding protein (C4bp).

Produktmerkmale: Synonyms: C4BPA, C4BP, Proline-rich protein, PRP

Aufreinigung: Affinity Chromatography on Protein A.

Immunogen: Native Human C4 binding protein. Genename: C4BP

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Borate buffered saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu C4BPA

Target: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Andere Bezeichnung: C4b-Binding Protein alpha

Hintergrund: There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.Synonyms: C4BP, C4BPA, PRP, Proline-rich protein

Gen-ID: 722

UniProt: P04003

Pathways: Komplementsystem