C3 Antikörper

Produktnummer ABIN181107

Produktdetails anti-C3 Antikörper

Target: C3 (Complement Component 3 (C3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Flow Cytometry (FACS)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: CPAMD1, Complement component 3, C3 and PZP-like alpha-2-macroglobulindomain-containing protein 1

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Purified C3d from Human plasma

Klon: 053A-1149-3-1-4 (1003)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot (1/5000). Flow Cytometry. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Borate buffered saline, pH 8.4, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu C3

Target: C3 (Complement Component 3 (C3))

Andere Bezeichnung: Complement C3 (C3 Produkte)

Synonyme: AHUS5 antikoerper, ARMD9 antikoerper, ASP antikoerper, C3a antikoerper, C3b antikoerper, CPAMD1 antikoerper, AI255234 antikoerper, HSE-MSF antikoerper, Plp antikoerper, C3 antikoerper, C3-1 antikoerper, sb:cb26 antikoerper, si:dkey-76b14.4 antikoerper, wu:fi34b03 antikoerper, wu:fj86e11 antikoerper, C3d antikoerper, asp antikoerper, cpamd1 antikoerper, c3 antikoerper, complement C3 antikoerper, complement component 3 antikoerper, complement component c3a, duplicate 1 antikoerper, complement component 3 L homeolog antikoerper, complement component C3 antikoerper, complement C3-like antikoerper, C3 antikoerper, c3a.1 antikoerper, c3.L antikoerper, LOC443475 antikoerper, c3 antikoerper, c3-1 antikoerper, LOC100060539 antikoerper

Hintergrund: C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3

UniProt: P01024

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling