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C3 Antikörper

C3 Reaktivität: Human WB, EIA Wirt: Maus Monoclonal 01-10-21 unconjugated
Produktnummer ABIN181105
  • Target Alle C3 Antikörper anzeigen
    C3 (Complement Component 3 (C3))
    Reaktivität
    • 93
    • 57
    • 35
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    Human
    Wirt
    • 72
    • 47
    • 27
    • 8
    • 7
    • 6
    Maus
    Klonalität
    • 129
    • 37
    Monoklonal
    Konjugat
    • 74
    • 24
    • 24
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser C3 Antikörper ist unkonjugiert
    Applikation
    • 109
    • 54
    • 40
    • 35
    • 33
    • 30
    • 30
    • 29
    • 23
    • 18
    • 14
    • 13
    • 13
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognises 9 kDa complement component 3a (C3a) which is present in the blood serum. The antibody shows minimal reactivity with other complement proteins in radioimmunoassays and haemagglutination.
    Produktmerkmale
    Synonyms: CPAMD1, Complement component 3, C3 and PZP-like alpha-2-macroglobulindomain-containing protein 1
    Aufreinigung
    Affinity Chromatography on Protein A
    Immunogen
    Native purified Human C3a. Genename: C3a
    Klon
    01-10-21
    Isotyp
    IgG1
    Top Product
    Discover our top product C3 Primärantikörper
  • Applikationshinweise
    Western BLot. ELISA: 1/1500-1/6000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    Borate buffered saline, pH 8.2 containing 0.09 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    C3 (Complement Component 3 (C3))
    Andere Bezeichnung
    Complement C3 (C3 Produkte)
    Synonyme
    AHUS5 antikoerper, ARMD9 antikoerper, ASP antikoerper, C3a antikoerper, C3b antikoerper, CPAMD1 antikoerper, AI255234 antikoerper, HSE-MSF antikoerper, Plp antikoerper, C3 antikoerper, C3-1 antikoerper, sb:cb26 antikoerper, si:dkey-76b14.4 antikoerper, wu:fi34b03 antikoerper, wu:fj86e11 antikoerper, C3d antikoerper, asp antikoerper, cpamd1 antikoerper, c3 antikoerper, complement C3 antikoerper, complement component 3 antikoerper, complement component c3a, duplicate 1 antikoerper, complement component 3 L homeolog antikoerper, complement component C3 antikoerper, complement C3-like antikoerper, C3 antikoerper, c3a.1 antikoerper, c3.L antikoerper, LOC443475 antikoerper, c3 antikoerper, c3-1 antikoerper, LOC100060539 antikoerper
    Hintergrund
    C3a is generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3a and C3b, which is further degraded into iC3b and C3dg/C3d. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation. C3a mediates local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3a is expressed at significantly higher levels in colorectal cancer.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
    Gen-ID
    718
    UniProt
    P01024
    Pathways
    Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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