C1QA Antikörper

Produktnummer ABIN181104

Produktdetails anti-C1QA Antikörper

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C1QA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognises human complement component 1, q subcomponent (C1q), a 156 kDa secreted protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: Complement C1q, Complement 1q

Aufreinigung: Affinity Chromatography on Protein A.

Immunogen: Binds globular head domain of C1q, purified from human plasma. Genename: C1QA, C1QB, C1QC

Klon: 3R9-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Flow Cytometry. Immunohistochemistry on Frozen Sections: It has been reported that this antibody worksvery well on acetone-fixed, frozen renal biopsies at a dilution of 1/500-1/600. Strongstaining was observed in the glomeruli and in some cases the peritubular capillary(potentially clinically significant). Recommended Positive Control: Kidney tissue from patients with streptococalglomerulonephritis.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Borate Buffered Saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Andere Bezeichnung: C1q A Subunit (C1QA Produkte)

Synonyme: zgc:109903 antikoerper, C1QA antikoerper, AI255395 antikoerper, C1q antikoerper, complement C1q A chain antikoerper, complement component 1, q subcomponent, A chain antikoerper, complement component 1, q subcomponent, alpha polypeptide antikoerper, C1QA antikoerper, c1qa antikoerper, C1qa antikoerper

Hintergrund: C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.Synonyms: Complement 1q, Complement C1q

Gen-ID: 712

UniProt: P02745

Pathways: Komplementsystem