Thyroglobulin Antikörper

Produktnummer ABIN180965

Der Maus Monoklonal Anti-Thyroglobulin-Antikörper wurde für EIA und ELISA (Capture) validiert. Er ist geeignet, Thyroglobulin in Proben von Human zu detektieren.

Kurzübersicht für Thyroglobulin Antikörper (ABIN180965)

Target: Thyroglobulin (TG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Thyroglobulin Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Capture)

Klon: BGN-6E10

Produktdetails anti-Thyroglobulin Antikörper

Spezifität: Reacts with different epitope to clone BGN/6D7 (BM733) and can be used as the coated antibody in 2 site assay with this clone.

Produktmerkmale: Synonyms: Thyreoglobulin, TGN

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Purified Native Human Thyreoglobulin.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Thyroglobulin

Target: Thyroglobulin (TG)

Hintergrund: Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.Synonyms: TGN, Thyreoglobulin

Gen-ID: 7038

UniProt: P01266

Pathways: Thyroid Hormone Synthesis