EPH Receptor A2 Antikörper

Produktnummer ABIN179724

Dieses Anti-EPH Receptor A2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von EPH Receptor A2 in FACS, IF und cELISA. Geeignet für Human.

Kurzübersicht für EPH Receptor A2 Antikörper (ABIN179724)

Target: EPH Receptor A2 (EPHA2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor A2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Cell-ELISA (cELISA)

Klon: Kalpha-5H5

Produktdetails anti-EPH Receptor A2 Antikörper

Spezifität: Anti-human EphA2

Aufreinigung: Protein G

Immunogen: genetic immunisation with cDNA encoding human EphA2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Kommentare:

Synonyms: Eph receptor tyrosine kinase A2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Details zu EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Andere Bezeichnung: EPHA2

Hintergrund: EphA2 (Ephrin receptor tyrosine kinase A2) belongs to the Ephrin tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells. Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis. The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it represent an attractive potential target for drug design.

UniProt: P29317

Pathways: RTK Signalweg