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LRRC32 Antikörper (AA 296-308)

LRRC32 Reaktivität: Human FACS Wirt: Maus Monoclonal 227G6 unconjugated
Produktnummer ABIN1742450
  • Target Alle LRRC32 Antikörper anzeigen
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 296-308
    Reaktivität
    • 29
    • 13
    • 9
    • 1
    Human
    Wirt
    • 20
    • 15
    • 4
    • 1
    Maus
    Klonalität
    • 21
    • 19
    Monoklonal
    Konjugat
    • 20
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser LRRC32 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 16
    • 15
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Specific for GARP.
    Aufreinigung
    purified IgG. Azide was added before lyophilization.
    Immunogen
    Synthetic peptide (aa 296-308 of human GARP) coupled to KLH via N-terminal added cysteine.
    Klon
    227G6
    Isotyp
    IgG3
    Top Product
    Discover our top product LRRC32 Primärantikörper
  • Applikationshinweise
    WB: not recommended
    IP: not tested yet
    ICC: not tested yet
    IHC: not tested yet
    FACS: 1 : 100 up to 1 : 1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    For reconstitution add 100 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
    Buffer
    PBS, 0.02% sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Cuende, Liénart, Dedobbeleer, van der Woning, De Boeck, Stockis, Huygens, Colau, Somja, Delvenne, Hannon, Baron, Dumoutier, Renauld, De Haard, Saunders, Coulie, Lucas: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." in: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).

    Rappl, Pabst, Riemann, Schmidt, Wickenhauser, Schütte, Hombach, Seliger, Grohé, Abken: "Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation." in: Clinical immunology (Orlando, Fla.), Vol. 140, Issue 1, pp. 71-83, (2011) (PubMed).

    Probst-Kepper, Geffers, Kröger, Viegas, Erck, Hecht, Lünsdorf, Roubin, Moharregh-Khiabani, Wagner, Ocklenburg, Jeron, Garritsen, Arstila, Kekäläinen, Balling, Hauser, Buer, Weiss: "GARP: a key receptor controlling FOXP3 in human regulatory T cells." in: Journal of cellular and molecular medicine, Vol. 13, Issue 9B, pp. 3343-57, (2010) (PubMed).

  • Target
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Andere Bezeichnung
    GARP (LRRC32 Produkte)
    Synonyme
    D11S833E antikoerper, GARP antikoerper, AI426318 antikoerper, D11S833Eh antikoerper, D7H11S833E antikoerper, EG434215 antikoerper, Garp antikoerper, leucine rich repeat containing 32 antikoerper, LRRC32 antikoerper, Lrrc32 antikoerper
    Hintergrund
    Synonyms: LRRC 32
    Pathways
    Activated T Cell Proliferation
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