TP53INP1 Antikörper (AA 1-14)

Produktnummer ABIN1737783

Dieses Anti-TP53INP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TP53INP1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TP53INP1 Antikörper (AA 1-14) (ABIN1737783)

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53INP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TP53INP1 Antikörper

Bindungsspezifität: AA 1-14

Spezifität: Reacts with human p53DINP1. Cross-reacts with mouse and rat protein.

Aufreinigung: Purified

Immunogen: Peptide corresponding to aa 1-14 of human p53DINP1. This sequence is identical in p53DINP1 alpha and beta and differs from that of mouse p53DINP1 by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB: 1-2 μg/mL

Positive control: Human lung tissue

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Haltbarkeit: 6 months

Details zu TP53INP1

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Andere Bezeichnung: p53DINP1

Hintergrund: Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.

Tumor protein p53-inducible nuclear protein 1 Stress-induced protein p53-dependent damage-inducible nuclear protein 1, p53DINP1 Gene name: TP53INP1, P53DINP1, SIP

Gen-ID: 94241

UniProt: Q96A56