F12 Antikörper
Kurzübersicht für F12 Antikörper (ABIN1734212)
Target
Alle F12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Reacts with human F12 / Factor XII
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Kreuzreaktivität (Details)
- Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma.
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Aufreinigung
- Purified
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Immunogen
- Activated human Factor XII (F XIIa) purified from plasma.
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Isotyp
- IgG
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Applikationshinweise
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Working dilution: IHC-P (5 μg/mL)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 10 mM HEPES, pH 7.4, 0.15 M NaCl, 50 % glycerol.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Long term: -20°C, Short term: +4°C. Avoid repeat freeze-thaw cycles.
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- F12 (Coagulation Factor XII (F12))
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Andere Bezeichnung
- F12 / Factor XII
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Hintergrund
- Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
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Pathways
- Komplementsystem
Target
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