ERK1/2 Antikörper

Produktnummer ABIN1734127

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ERK1/2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Huhn, Xenopus laevis, Säugetier und Drosophila melanogaster.

Kurzübersicht für ERK1/2 Antikörper (ABIN1734127)

Target: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Reaktivität: Human, Maus, Huhn, Xenopus laevis, Säugetier, Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERK1/2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ERK1/2 Antikörper

Spezifität: Reacts with human Erk1 and Erk2. Cross-reacts with mouse, rat, chicken, sheep, bovine, drosophila and xenopus protein.

Aufreinigung: Serum

Immunogen: 35 amino acid synthetic peptide corresponding to ERK1 conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:5000

Positive control: HeLa cell

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Haltbarkeit: 6 months

Details zu ERK1/2

Target: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Andere Bezeichnung: Erk1 + Erk2

Hintergrund: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

Mitogen-activated protein kinase 3 & Mitogen-activated protein kinase 1 Extracellular signal-regulated kinase 1 & Extracellular signal-regulated kinase 3 ERK-1 & ERK-2 Gene name: MAPK3, MAPK1

UniProt: P27361, P28482