ATG4B Antikörper
Kurzübersicht für ATG4B Antikörper (ABIN1732017)
Target
Alle ATG4B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- Reacts with human ATG4B
-
Kreuzreaktivität
- Maus, Zebrafisch, Huhn, Ratte (Rattus)
-
Kreuzreaktivität (Details)
- Cross reacts with chicken, xenopus, mouse, pufferfish, rat and zebrafish protein.
-
Aufreinigung
- Purified (protein G)
-
Immunogen
- Synthetic peptide from human ATG4B.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (10 μg/mL), WB (1 - 3 μg/mL) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- PBS, 0.2 % gelatin, Sodium azide 0.05 %
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
-
-
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
-
Andere Bezeichnung
- ATG4B
-
Hintergrund
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.
-
Gen-ID
- 23192
-
Pathways
- Autophagie
Target
-