GABBR2 Antikörper (AA 319-483)

Produktnummer ABIN1724937

Dieses Anti-GABBR2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von GABBR2 in IHC, ELISA und ICC. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für GABBR2 Antikörper (AA 319-483) (ABIN1724937)

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GABBR2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Klon: 5G7F7

Produktdetails anti-GABBR2 Antikörper

Bindungsspezifität: AA 319-483

Verwendungszweck: GABBR2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-GABBR2 Antikörper (ABIN1724937)

Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).

Details zu GABBR2

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Andere Bezeichnung: GABBR2

Hintergrund: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

Molekulargewicht: 105.8 kDa

Gen-ID: 9568

UniProt: O75899

Pathways: cAMP Metabolic Process