Syndecan 1 Antikörper (AA 28-171)

Produktnummer ABIN1724936

Der Maus Monoklonal Anti-Syndecan 1-Antikörper wurde für WB, IHC, ELISA, FACS und ICC validiert. Er ist geeignet, Syndecan 1 in Proben von Human und Maus zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Syndecan 1 Antikörper (AA 28-171) (ABIN1724936)

Target: Syndecan 1 (SDC1)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Syndecan 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 1A3H4

Produktdetails anti-Syndecan 1 Antikörper

Bindungsspezifität: AA 28-171

Verwendungszweck: SDC1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Syndecan 1 Antikörper (ABIN1724936)

Nunez, Siegal, Reddy, Wei: "CD138 (syndecan-1) expression in bone-forming tumors." in: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).

Karasneh, Ali, Shukla: "An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread." in: PLoS ONE, Vol. 6, Issue 9, pp. e25252, (2011) (PubMed).

Details zu Syndecan 1

Target: Syndecan 1 (SDC1)

Andere Bezeichnung: SDC1

Hintergrund: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Molekulargewicht: 32.5 kDa

Gen-ID: 6382

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism