Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-CDX2 Antikörper wird verwendet zum Nachweis von CDX2 in Proben von Human. Er wurde validiert für ELISA.
CDX2
Reaktivität: Human
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified antibody in PBS with 0.05 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Lee, Vogt, Hsiao, Osunkoya: "CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules." in: Tumour biology, Vol. 33, Issue 6, pp. 2185-8, (2012) (PubMed).
Liu, Zhang, Zhan, Brock, Herman, Guo: "CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer." in: Cancer biology & therapy, Vol. 13, Issue 12, pp. 1152-7, (2012) (PubMed).
Target
CDX2
(Caudal Type Homeobox 2 (CDX2))
Andere Bezeichnung
CDX2
Hintergrund
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.